I load the Hornady 52 gr A-max in mine at 3700/3800 fps (chronographed) with either Varget or WW760. My 22-250 has a 1:14 twist so it stabilizes the lighter bullets very well. You didn't say what manufacturers rifle/model you are loading for so it is hard to say what gr bullet would be best in your .22-250. I would load as light as your rifling will let you and still staying accurate. I'm sure a bullet in the mid 50's gr area would work fine. 60 gr and larger bullets are ok if you want to use it on deer sized game but there are better calibers for that. You certainly don't need them for the varmints the .22-250 was designed for.
By the way, hunterjoe, that's a fairly light load in your .22-250 but as long as it's accurate that's what matters. My .22-250 likes them on the hotter side.