At one time, the 150 gr. 30 caliber bullet was the chosen weight for deer, and the 180gr. was for the bigger stuff. They'd zip right through the light -bodied deer without expanding.
Since that bit of wisdom was "the last word", I'm sure there have been a few changes in bullets, and the 165 gr. has been invented, which would seem to give the best of both worlds.
All the talk of "versatility", using bullets from 100-220 gr. is just so much wind in the willows, IMO. Pick a good bullet, (one that won't fly back and shoot your hat off) find a good load for it, sight it in and concentrate on putting it where it needs to go.
Like a buddy of mine, who was a self-proclaimed "guru". We were hunting one day, and he saw his only good deer of the day. His scope was set on 7X, but no, he just HAD to have it set EXACTLY
on 4X, and was diddle-fritzin' with the power ring when the deer departed. Good one, Dude!
Hunting season is not the time to have to factor in variables. That needs to be settled before you get in the car to head for the high lonesome.
BE CONFIDENT of where your rifle shoots beforehand...it pays dividends.
I only saw one, that day, but by the time I shouldered my rifle , all I saw was his heels. We got rained on, snowed on, fogged in, cold, wet, hungry...altogether a good day!